Allergens and Allergen Immunotherapy by Richard F. Lockey, Dennis K. Ledford

By Richard F. Lockey, Dennis K. Ledford

This 5th version of the bestselling Allergens and Allergen Immunotherapy is now thoroughly up-to-date and revised to incorporate subcutaneous, sublingual, and oral immunomodulator remedies of allergic disease.

The redesigned booklet keeps to supply complete insurance of every kind of allergens and allergen vaccines, giving clinicians the fundamental info they should appropriately make a analysis and provide the absolute best remedies.

The 5th variation includes many new and revised chapters―particularly within the fields of epidermis testing―and vast updates to the sublingual and oral immunotherapy chapters.

Key positive factors:

  • Comprehensive – covers an unlimited variety of allergens and allergen immunotherapies, offering the entire worthwhile details in a single volume
  • Synoptic – provides the fundamental info utilizing figures and tables for immediate entry
  • Up-to-date – contains the very most up-to-date details on subcutaneous, sublingual and oral allergen immunotherapies to provide the absolute best treatments
  • Reliable – presents easy details that each one clinicians want to know approximately cross-reactivity between allergens and the way it affects prognosis and remedy, in addition to the foremost info essential to perform any kind of immunotherapy in a secure and powerful demeanour
  • Supplemental varieties – includes template kinds that may be utilized by the clinician in day-by-day practice

The 5th version of this vintage textual content is still an important touchstone for any practitioner who conducts pores and skin checks and prescribes subcutaneous, sublingual, and oral immunotherapies.

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Additional info for Allergens and Allergen Immunotherapy

Sample text

Depot-like immunogenic materials were prepared to provide a slow, continuous release of allergen from injection sites. The first attempt used ground raw pollen suspended in olive oil [107]. Because particulate bacterial vaccines and modified toxoid proved to be effective immunogens, soluble pollen allergen vaccines were converted to particulate suspensions by alum precipitation and alum adsorption [108,109]. Other modifications included acetylation, heat, and formalin treatment [109], precipitation by tannic [110] and hydrochloric acids [111], and mixture with gelatin [112].

S. cities [53]. Rapid dissemination and application of the newly developed methods for identification of specific agents of hypersensitivity and desensitization therapy for hay fever and asthma patients engendered a new set of problems and questions complicating logical approaches well into the 1940s [53]. The era of grant-supported full-time institutional-based academic and research positions in allergy and clinical immunology was then still some three to four decades away. Meanwhile, awaiting definition through research-generated data, there developed a wide variability in ideas, criteria for indications, usage of materials, and methods and design of injection treatment plans.

Natural history of asthma and allergic disease and (ii) largescale clinical trials from which construct critical criteria for exact indications, and use of materials and methods by which immunotherapeutic regimens can be properly evaluated. Second is the awareness of the enormous impact and influence that allergen immunotherapy had on the launching, development, and continuation of allergy as a medical specialty. For 40–50 years following the original description of skin test and hyposensitization techniques, these modalities served as the mainstays of allergy when there was little else to offer in the way of adequate and feasible management.

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